RAF Typhoon jets have operated alongside France's air force in a coordinated attack on an hidden munitions depot in Syrian territory operated by the IS group, per a report from the UK's MoD.
The site, located using surveillance, was thought to be containing munitions and bombs, the announcement noted, and was located in mountainous terrain just to the north of the ancient city of Palmyra in the heart of Syria.
"The RAF jets used precision-guided Paveway IV munitions to target a number of entry passages down to the facility... initial indications indicate the strike was effective," the ministry announced.
There was no evidence of any civilian impact in the operation late on Saturday and each participating jet made a safe return, the defence officials confirmed.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
The Islamic State group - also known as the so-called Islamic State - established jihadist rule over large swathes of Syria and Iraq prior to its 2019 collapse.
"This operation underscores British leadership, and determination to work closely with our partners, to eradicate any resurgence of IS and their dangerous and violent ideologies in the area," Britain's Defence Chief the Defence Secretary remarked.
British military aircraft have carried out surveillance missions over Syria to "prevent any efforts to regroup" of the group following its military defeat at the battle of Baghuz in the year 2019, the MoD reported.
"I extend gratitude to all the members of British forces involved in this mission for their professionalism and their valour," Healey added. "They were among numerous British troops stationed over Christmas and New Year. This action, to take out militants who threaten our safety, shows how our armed forces are prepared to act, throughout the year, protecting the UK within its borders and strong abroad."
During December, the United States armed forces executed what it called a "massive strike" on Daesh sites in the country, subsequent to an attack resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The U.N. reports Daesh still has an estimated 5,000 to 7,000 fighters in Iraq and Syria.